TRIB3 Polyclonal Antibody | Invitrogen PA5-15480 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRIB3 Polyclonal Antibody

catalog :

PA5-15480

quantity :

400 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

citations: 2

Reference
Li K, Wang F, Yang Z, Zhang T, Yuan Y, Zhao C, et al. TRIB3 promotes MYC-associated lymphoma development through suppression of UBE3B-mediated MYC degradation. Nat Commun. 2020;11:6316 pubmed publisher
Yu J, Sun W, Wang Z, Liang X, Hua F, Li K, et al. TRIB3 supports breast cancer stemness by suppressing FOXO1 degradation and enhancing SOX2 transcription. Nat Commun. 2019;10:5720 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TRIB3 Polyclonal Antibody

Catalog # :

PA5-15480

Quantity :

400 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

A novel inhibitor of cell division, Tribbles, blocks mitosis at a critical point in Drosophila morphogenesis. Recently, mammalian homologues of Tribbles (Trbs) have been identified that control mitogen-activated protein kinase (MAPK) activity. TRIB3 also known as TRB-3, SINK, and SKIP3 is a member of Trbs family. Overexpression of this protein inhibits NF-kB-dependent transcription induced by tumor necrosis factor (TNF) stimulation or its downstream signaling proteins but does not inhibit NF-kB translocation to the nucleus and binding to DNA. TRIB3/SKIP3 is also overexpressed in multiple human tumors and is regulated by hypoxia.

Immunogen :

KLH conjugated synthetic peptide between 301-331 amino acids from the C-terminal region of human TRIB3

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

C20orf97; DJ1103G7.3; Ifld2; induced in fatty liver dystrophy 2; kinase; Neuronal cell death Inducible Putative Kinase; neuronal cell death-inducible putative kinase; Nipk; p65-interacting inhibitor of NF-kappaB; p65-interacting inhibitor of NF-kappa-B; SINK; SKIP3; Trb3; TRB-3; TRIB3; Tribbles 3; Tribbles homolog 3; tribbles homolog 3 (Drosophila); tribbles pseudokinase 3