PI4K2A Polyclonal Antibody | Invitrogen PA5-15275 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PI4K2A Polyclonal Antibody

catalog :

PA5-15275

quantity :

400 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Shi L, Hines T, Bergson C, Smith D. Coupling of microtubule motors with AP-3 generated organelles in axons by NEEP21 family member calcyon. Mol Biol Cell. 2018;29:2055-2068 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PI4K2A Polyclonal Antibody

Catalog # :

PA5-15275

Quantity :

400 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Protein G

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

PI4K2A (PI4K2 alpha) lipid kinase or phosphatidylinositol 4-kinase type 2 alpha is involved in the formation of phosphatidylinositolpolyphosphates (PtdInsPs) which are centrally involved in many biologic processes ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4K2A phosphorylates PtdIns at the D-4 position which is an essential step in the biosynthesis of PtdInsPs. PI4K2A is a novel regulator of tumor growth by its action on angiogenesis and HIF-1alpha regulation. PI4K2A generates PtdIns4P-rich domains within the Golgi which regulate targeting of clathrin adaptor AP-1 complexes. PI4K2A is also required for Wnt to regulate LRP6 phosphorylation.

Immunogen :

KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PI4K2A (PI4K II)

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000

Aliases :

55 kDa type II phosphatidylinositol 4-kinase; null; phosphatidylinositol 4-kinase; phosphatidylinositol 4-kinase type 2 alpha; phosphatidylinositol 4-kinase type 2-alpha; phosphatidylinositol 4-kinase type II; phosphatidylinositol 4-kinase type II (PI4KII); phosphatidylinositol 4-kinase type II-alpha; Pi4k2; PI4K2A; Pi4kii; PIK42A