MEK5 Polyclonal Antibody | Invitrogen PA5-15083 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MEK5 Polyclonal Antibody

catalog :

PA5-15083

quantity :

400 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Craig J, Miller J, Rayavarapu R, Hong Z, Bulut G, Zhuang W, et al. MEKK3-MEK5-ERK5 signaling promotes mitochondrial degradation. Cell Death Discov. 2020;6:107 pubmed publisher

product information

Product Type :

Antibody

Product Name :

MEK5 Polyclonal Antibody

Catalog # :

PA5-15083

Quantity :

400 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography, Protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

MAP2K5 (MEK5) serine/threonine kinase (mitogen-activated protein kinase 5) or MEK5 is a dual specificity protein kinase that belongs to the MAP kinase family which specifically interacts with and activates MAPK7/ERK5. MAP2K5 itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation. The rs3743354 polymorphism in the MAP2K5 promoter may affect the risk of developing colorectal cancer (CRC).

Immunogen :

KLH conjugated synthetic peptide between 127-156 amino acids from human MAP2K5

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1,000

Aliases :

AI324775; AI428457; Dual specificity mitogen-activated protein kinase kinase 5; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPK/ERK kinese 5; MAPKK 5; Mapkk5; MEK 5; MEK5; mitogen activated protein kinase kinase 5; mitogen-activated protein kinase kinase 5; Mkk5; PRKMK5