SHISA7 Polyclonal Antibody | Invitrogen PA5-144065 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SHISA7 Polyclonal Antibody

catalog :

PA5-144065

quantity :

100 ug

price :

US 394.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

SHISA7 Polyclonal Antibody

Catalog # :

PA5-144065

Quantity :

100 ug

Price :

US 394.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 0.1-0.5 ug/mL, Western Blot: 0.25-0.5 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

The SHISA7 gene encodes a member of the Shisa family proteins, which are involved in the regulation of signaling pathways critical for embryonic development and cellular communication. SHISA7 is particularly influential in modulating synaptic transmission in the central nervous system. It plays a key role in regulating the surface expression and activity of AMPA-type glutamate receptors, which are crucial for fast excitatory neurotransmission and synaptic plasticity in the brain. By controlling the trafficking and localization of these receptors, SHISA7 impacts synaptic strength and neuronal excitability, affecting learning, memory, and other cognitive functions. The functional regulation by SHISA7 of AMPA receptors can have implications for neuropsychiatric disorders, where dysregulation of synaptic transmission is a common feature. Understanding SHISA7's role in synaptic modulation could lead to insights into the mechanisms underlying cognitive processes and the development of therapeutic strategies for neurological conditions.

Immunogen :

E.coli-derived human SHISA7 recombinant protein (Position: Y308-E535).

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 0.1-0.5 ug/mL, Western Blot: 0.25-0.5 ug/mL

Aliases :

CKAMP59; Cystine-knot AMPAR modulating protein of 59 kDa; hCG_2039146; Protein shisa-6-like; Protein shisa-7; shisa family member 7; shisa homolog 7; SHISA7; UPF0626 protein A