This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TMEM52B Polyclonal Antibody
catalog :
PA5-144059
quantity :
100 ug
price :
US 394.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, flow cytometry
product information
Product Type :
Antibody
Product Name :
TMEM52B Polyclonal Antibody
Catalog # :
PA5-144059
Quantity :
100 ug
Price :
US 394.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Non-human primate, Rat
Applications :
ELISA: 0.1-0.5 ug/mL, Flow Cytometry: 1-3 ug/1x10^6 cells, Western Blot: 0.25-0.5 ug/mL
Species :
Human, Mouse, Non-human primate, Rat
Isotype :
IgG
Storage :
-20 C
Description :
The TMEM52B gene encodes a transmembrane protein that is widely expressed across various normal human tissues, suggesting its fundamental role in maintaining cellular integrity. TMEM52B is part of the transmembrane protein (TMEM) family, which contains proteins that span biological membranes, including the lipid bilayer of the plasma membrane and organelle membranes. This gene is notably involved in tumor biology, where it modulates cancer cell survival and invasion. Studies have shown that suppression of TMEM52B expression can enhance the aggressiveness of cancer cells, indicating its potential as a tumor suppressor gene. Specifically, TMEM52B isoforms such as P18 and P20 have been found to differentially influence tumor dynamics, particularly in the context of nasopharyngeal carcinoma (NPC). While its exact molecular mechanisms remain largely unknown, the regulation of TMEM52B is crucial for controlling tumor growth and metastasis. Therefore, understanding its role could provide insights into therapeutic strategies aimed at curbing cancer progression.
Immunogen :
E.coli-derived human TMEM52B recombinant protein (Position: T22-N183).
Format :
Lyophilized
Applications w/Dilutions :
ELISA: 0.1-0.5 ug/mL, Flow Cytometry: 1-3 ug/1x10^6 cells, Western Blot: 0.25-0.5 ug/mL
Aliases :
C12orf59; TMEM52B; Transmembrane protein 52B; UNQ5927/PRO19821
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA