TRANK1 Polyclonal Antibody | Invitrogen PA5-144000 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRANK1 Polyclonal Antibody

catalog :

PA5-144000

quantity :

100 ug

price :

US 394.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

TRANK1 Polyclonal Antibody

Catalog # :

PA5-144000

Quantity :

100 ug

Price :

US 394.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

ELISA: 0.1-0.5 ug/mL, Flow Cytometry: 1-3 ug/1x10^6 cells, Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 2-5 ug/mL, Western Blot: 0.25-0.5 ug/mL

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

The TRANK1 gene encodes the tetratricopeptide repeat and ankyrin repeat containing 1 protein, which has been associated with neurodevelopmental and psychiatric conditions, particularly bipolar disorder and schizophrenia. Located on chromosome 9, this gene contains both tetratricopeptide repeats and ankyrin repeats, which contribute to protein-protein interactions and structural stability. TRANK1 is thought to possibly participate in cellular functions related to brain development and synaptic transmission, impacting neuronal signaling and cognitive processes. Genetic studies have identified variations in the TRANK1 gene that may alter its expression, influencing susceptibility to bipolar disorder by modulating pathways related to neurotransmitter regulation and neuroplasticity. The specific mechanisms by which TRANK1 influences psychiatric disorders remain under investigation, but it is hypothesized that TRANK1's interaction with other proteins involved in signal transduction could be pivotal. Given its potential linkage to complex neurological disorders, TRANK1 serves as a significant focal point for studies aiming to understand the genetic basis of these conditions and develop targeted interventions.

Immunogen :

E.coli-derived human TRANK1 recombinant protein (Position: K1926-R2763).

Format :

Lyophilized

Applications w/Dilutions :

ELISA: 0.1-0.5 ug/mL, Flow Cytometry: 1-3 ug/1x10^6 cells, Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 2-5 ug/mL, Western Blot: 0.25-0.5 ug/mL

Aliases :

KIAA0342; LBA1; Lupus brain antigen 1 homolog; tetratricopeptide repeat and ankyrin repeat containing 1; TPR and ankyrin repeat-containing protein 1; TRANK1