Vimentin Polyclonal Antibody | Invitrogen PA5-143558 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Vimentin Polyclonal Antibody

catalog :

PA5-143558

quantity :

500 uL

price :

US 1614.00

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine, pigs , domestic horse

application :

western blot, immunohistochemistry, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

Vimentin Polyclonal Antibody

Catalog # :

PA5-143558

Quantity :

500 uL

Price :

US 1614.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Goat

Reactivity :

Bovine, Equine, Human, Mouse, Non-human primate, Porcine, Rat

Applications :

Immunocytochemistry: 1:500-1:1,000, Immunohistochemistry: Assay-dependent, Western Blot: 1:5,000

Species :

Bovine, Equine, Human, Mouse, Non-human primate, Porcine, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.

Immunogen :

Recombinant human vimentin expressed in and purified from E. coli

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:500-1:1,000, Immunohistochemistry: Assay-dependent, Western Blot: 1:5,000

Aliases :

cb28; class-III intermediate microfilament; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; VIM; VIME; Vimentin; vimentin C-terminus