This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Haptoglobin beta Polyclonal Antibody
catalog :
PA5-142825
quantity :
100 ug
price :
US 444.00
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, pigs
application :
western blot
product information
Product Type :
Antibody
Product Name :
Haptoglobin beta Polyclonal Antibody
Catalog # :
PA5-142825
Quantity :
100 ug
Price :
US 444.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation
Host :
Goat
Reactivity :
Human, Porcine
Applications :
Western Blot: 0.1-0.3 ug/mL
Species :
Human, Porcine
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity, and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. [PMID: 21248165]. The uncleaved form of allele alpha-2 (2-2), known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens. [PMID: 21248165]
Immunogen :
Peptide with sequence C-STVPEKKTPKSP.
Format :
Liquid
Applications w/Dilutions :
Western Blot: 0.1-0.3 ug/mL
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA