This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PTMA Polyclonal Antibody
catalog :
PA5-142436
quantity :
100 ug
price :
US 444.00
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
PTMA Polyclonal Antibody
Catalog # :
PA5-142436
Quantity :
100 ug
Price :
US 444.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation
Host :
Goat
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 3.75 ug/mL, Western Blot: 0.2 ug/mL
Species :
Human
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The thymus gland produces several hormones or hormone-like substances which are derived from a polypeptide precursor containing (in the rat) 113 amino acids and known as prothymosin-alpha. A peptide containing 28 amino acid residues, named thymosin-alpha-1, was originally isolated from calf thymosin fraction 5 and shown to restore various aspects of immune function in several in vitro and invivo test systems. Thymosin-alpha-1 was subsequently isolated from a similar fraction from human thymosin and reported to have the same amino acid sequence as bovine thymosin-alpha-1. In 2003, Jiang et al. identified a pathway that regulates mitochondria-initiated caspase activity. In this pathway, putative human HLA class II-associated protein (PHAP) promoted caspase-9 activation after apoptosome formation, whereas prothymosin-alpha-1 negatively regulated caspase-9 activation by inhibiting apoptosome formation.
Immunogen :
Peptide with sequence C-DVDTKKQKTDEDD.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 3.75 ug/mL, Western Blot: 0.2 ug/mL
Aliases :
alpha-prothymosin; gene sequence 28; prothymosin alpha; prothymosin alpha protein; Prothymosin alpha, N-terminally processed; prothymosin, alpha; prothymosin-alpha; PTMA; Thym; thymosin; Thymosin alpha; Thymosin alpha-1; TMSA; TMSB4; TMSB4X
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA