This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TDP1 Polyclonal Antibody
catalog :
PA5-142392
quantity :
100 ug
price :
US 444.00
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
Product Type :
Antibody
Product Name :
TDP1 Polyclonal Antibody
Catalog # :
PA5-142392
Quantity :
100 ug
Price :
US 444.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation
Host :
Goat
Reactivity :
Human
Applications :
Western Blot: 1-3 ug/mL
Species :
Human
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.
Immunogen :
Peptide with sequence C-PNDGTAQRTENHG.
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1-3 ug/mL
Aliases :
2810481F14Rik; 4921509N21Rik; AI838772; AW493413; E430034L06Rik; MLZ-501; protein expressed in male leptotene and zygotene spermatocytes 501; SCAN1; Tdp1; Tyr-DNA phosphodiesterase 1; tyrosyl-DNA phodphodiesterase 1; tyrosyl-DNA phosphodiesterase 1; Tyrosyl-DNA phosphodiesterase 1-like protein
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA