Parvalbumin Polyclonal Antibody, Biotin | Invitrogen PA5-142152 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Parvalbumin Polyclonal Antibody, Biotin

catalog :

PA5-142152

quantity :

100 ug

price :

US 444.00

clonality :

polyclonal

host :

domestic goat

conjugate :

biotin

reactivity :

human, rat

application :

western blot

product information

Product Type :

Antibody

Product Name :

Parvalbumin Polyclonal Antibody, Biotin

Catalog # :

PA5-142152

Quantity :

100 ug

Price :

US 444.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation

Host :

Goat

Reactivity :

Human, Rat

Applications :

Western Blot: 1-3 ug/mL

Species :

Human, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis (ALS) patents, parvalbumin immunoreactivity is specifically absent from neuron populations lost early in ALS.

Immunogen :

Peptide with sequence C-GVDEFSTLVAES (aa 99-110).

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1-3 ug/mL

Aliases :

D22S749; HGNC:9704; MGC116759; PALB1; Parv; parvalbumin; Parvalbumin (calcium binding protein); parvalbumin alpha; PV; Pva; PVALB