ACVR1 Polyclonal Antibody | Invitrogen PA5-13881 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ACVR1 Polyclonal Antibody

catalog :

PA5-13881

quantity :

400 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Seo D, Jung S, Park J, Lee J, Ha J, Kim M, et al. The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway. EBioMedicine. 2019;49:55-71 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ACVR1 Polyclonal Antibody

Catalog # :

PA5-13881

Quantity :

400 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Host :

Rabbit

Reactivity :

Human, Rat

Applications :

Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000

Species :

Human, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Activin A receptor, type I (ACVR1) belongs to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. ACVR1 signals a specific transcriptional response in concert with activin type II receptors. The ACVR1 gene encodes activin A type I receptor, which signals a particular transcriptional response in concert with activin type II receptors. Mutations in ACVR1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.

Immunogen :

KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human Activin Receptor Type IA (ACVR1)

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000

Aliases :

activin A receptor type 1; activin A receptor type I; activin A receptor, type 1; activin A receptor, type I; activin A receptor, type II-like kinase 2; activin receptor I precursor; activin receptor type I; Activin receptor type-1; activin receptor-like kinase 2; activin type I receptor; ACTRI; ActR-I; ActRIA; Acvr; ACVR1; ACVR1A; ACVRLK2; ALK2; Alk-2; ALK2-B; Alk8; ATVR1; D330013D15Rik; FOP; hydroxyalkyl-protein kinase; serine/threonine-protein kinase receptor; serine/threonine-protein kinase receptor R1; SKR1; TGF-B superfamily receptor type I; Tgfb1; Tsk7L; TSK-7L; TSRI; TSR-I; type I TGF B receptor