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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytokeratin 4 Polyclonal Antibody
catalog :
PA5-13684
quantity :
400 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:100
Yokobori T, Suzuki S, Miyazaki T, Sohda M, Sakai M, Tanaka N, et al. Intestinal epithelial culture under an air-liquid interface: a tool for studying human and mouse esophagi. Dis Esophagus. 2016;29:843-847 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Cytokeratin 4 Polyclonal Antibody
Catalog # :
PA5-13684
Quantity :
400 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9-7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
Immunogen :
KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human KRT4
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000
Aliases :
57kd keratin; 57kDa keratin; AW108092; cb59; CK4; CK-4; CYK4; cytokeratin; cytokeratin 4; cytokeratin-4; Cytoskeletal 57 kDa keratin; etID20321.6; intermediate filament protein; K4; Kb4; keratin 4; keratin 4, type II; keratin 8; keratin complex 2, basic, gene 4; keratin, type II cytoskeletal 4; Keratin-4; Krt-2.4; Krt2-4; Krt4; krt4 {ECO:0000250; krt4 protein; krt8; type II basic cytokeratin; type II keratin Kb4; type-II keratin Kb4; UniProtKB:P19013}; WSN1; wu:fa91a11; wu:fd19e09; wu:fl23c09; zf-K8
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA