This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PRAME Polyclonal Antibody
catalog :
PA5-13679
quantity :
400 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 2
Reference
Ma H, Soderquist C, Marchi E, Scotto L, Bhagat G, O Connor O. Cancer testis antigen expression across T-cell lymphoma subtypes. Hematol Oncol. 2020;38:827-830 pubmed publisher
Al Khadairi G, Naik A, Thomas R, Al Sulaiti B, Rizly S, Decock J. PRAME promotes epithelial-to-mesenchymal transition in triple negative breast cancer. J Transl Med. 2019;17:9 pubmed publisher
product information
Product Type :
Antibody
Product Name :
PRAME Polyclonal Antibody
Catalog # :
PA5-13679
Quantity :
400 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography, Protein A
Host :
Rabbit
Reactivity :
Human
Applications :
Flow Cytometry: 1:25, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:2,000
Species :
Human
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene.
Immunogen :
KLH conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human MAPE
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:25, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:2,000
Aliases :
4930534P07Rik; cancer/testis antigen 130; CT130; MAPE; melanoma antigen preferentially expressed in tumors; OIP4; OIP-4; Opa-interacting protein 4; Opa-interacting protein OIP4; PRAME; preferentially expressed antigen in melanoma; preferentially expressed antigen of melanoma
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA