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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Decorin Polyclonal Antibody
catalog :
PA5-13538
quantity :
400 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 3b
  • western blot; mouse; 1:1000; fig 1b
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 3c
Karthikeyan S, Lantvit D, Chae D, Burdette J. Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface. Oncotarget. 2016;7:69871-69882 pubmed publisher
Liu J, Zhu S, Zeng L, Li J, Klionsky D, Kroemer G, et al. DCN released from ferroptotic cells ignites AGER-dependent immune responses. Autophagy. 2021;:1-14 pubmed publisher
Chamberlin T, Thompson V, Hillers Ziemer L, Walton B, Arendt L. Obesity reduces mammary epithelial cell TGFβ1 activity through macrophage-mediated extracellular matrix remodeling. FASEB J. 2020;34:8611-8624 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Decorin Polyclonal Antibody
Catalog # :
PA5-13538
Quantity :
400 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Flow Cytometry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Decorin is a member of the small, leucine-rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF-b. It is believed that decorin also plays a role in the cell cycle of chondrocytes. The decorin neoepitope fragment has a sequence of PKTLQE, and is generated by MMP-3 or ADAMTS-4 cleavage at Glu154-Leu155 of decorin core protein.
Immunogen :
KLH conjugated synthetic peptide between 122-150 amino acids from the central region of human DCN
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1,000
Aliases :
Bone proteoglycan II; CSCD; DC; Dcn; DCN protein; DCN1C; Decorin; decorin isoform a preproprotein; Dermatan sulfate proteoglycan-II; dermatan sulfate proteoglycan-II (decorin); dermatan sulphate proteoglycans II; Dermatan sulphate proteoglycans II (DSPG2); DSPG; DSPG2; mDcn; PG40; PGII; PGS2; PG-S2; proteoglycan core protein; proteoglycan core protein; binds type I collagen fibers and TGF-beta; decoron; similar to bone proteoglycan II; similar to decorin; SLRR1B; Small leucine rich protein 1B; small leucine-rich protein 1B; unnamed protein product
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA