Parkin Polyclonal Antibody | Invitrogen PA5-13399 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Parkin Polyclonal Antibody

catalog :

PA5-13399

quantity :

400 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 7

Reference
Read T, Cisterna B, Skruber K, Ahmadieh S, Lindamood H, Vitriol J, et al. The actin binding protein profilin 1 is critical for mitochondria function. bioRxiv. 2023;: pubmed publisher
Tian L, Jia Z, Yan Y, Jia Q, Shi W, Cui S, et al. Low-dose of caffeine alleviates high altitude pulmonary edema via regulating mitochondrial quality control process in AT1 cells. Front Pharmacol. 2023;14:1155414 pubmed publisher
Bertola N, Bruno S, Capanni C, Columbaro M, Mazzarello A, Corsolini F, et al. Altered Mitochondrial Dynamic in Lymphoblasts and Fibroblasts Mutated for FANCA-A Gene: The Central Role of DRP1. Int J Mol Sci. 2023;24: pubmed publisher
Tian P, Zhao L, Kim J, Li X, Liu C, Cui X, et al. Dual stimulus responsive borosilicate glass (BSG) scaffolds promote diabetic alveolar bone defectsrepair by modulating macrophage phenotype. Bioact Mater. 2023;26:231-248 pubmed publisher
Bertola N, Degan P, Cappelli E, Ravera S. Mutated FANCA Gene Role in the Modulation of Energy Metabolism and Mitochondrial Dynamics in Head and Neck Squamous Cell Carcinoma. Cells. 2022;11: pubmed publisher
Anzell A, Fogo G, Gurm Z, Raghunayakula S, Wider J, Maheras K, et al. Mitochondrial fission and mitophagy are independent mechanisms regulating ischemia/reperfusion injury in primary neurons. Cell Death Dis. 2021;12:475 pubmed publisher
Zheng J, He S, Zeng Z, Gu X, Cai L, Qi G. PMPCB Silencing Sensitizes HCC Tumor Cells to Sorafenib Therapy. Mol Ther. 2019;27:1784-1795 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Parkin Polyclonal Antibody

Catalog # :

PA5-13399

Quantity :

400 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography, Protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The precise function of Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.

Immunogen :

KLH conjugated synthetic peptide between 387-417 amino acids from the C-terminal region of human Parkin

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000

Aliases :

AAN12155.1; AR-JP; CG10523; CG10523-PB; CG10523-PC; Dmel CG10523; Dmel_CG10523; Dpark; dParkin; D-parkin; dpk; E3 ubiquitin ligase; E3 ubiquitin-protein ligase parkin; LPRS2; OTTHUMP00000017562; OTTHUMP00000017563; OTTHUMP00000017564; park; park1; PARK2; Parkin; parkin 2; parkin F; Parkin isoform 1; parkin protein; parkin RBR E3 ubiquitin protein ligase; Parkin RBR E3 ubiquitin-protein ligase; parkin variant SV5DEL; Parkinson disease (autosomal recessive, juvenile) 2, parkin; Parkinson disease protein 2; Parkinson juvenile disease protein 2; parkinson protein 2 E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase; parkinson protein 2, E3 ubiquitin protein ligase (parkin); park-PB; park-PC; PDJ; PK; Prkn; SD01679