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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MMP14 Polyclonal Antibody
catalog :
PA5-13183
quantity :
400 uL
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3b
Wolczyk D, Zaremba Czogalla M, Hryniewicz Jankowska A, Tabola R, Grabowski K, Sikorski A, et al. TNF-? promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts. Cell Oncol (Dordr). 2016;39:353-63 pubmed publisher
Sivaraj K, Majev P, Jeong H, Dharmalingam B, Zeuschner D, Schr xf6 der S, et al. Mesenchymal stromal cell-derived septoclasts resorb cartilage during developmental ossification and fracture healing. Nat Commun. 2022;13:571 pubmed publisher
Hryniewicz Jankowska A, Wierzbicki J, Tabola R, Stach K, Sossey Alaoui K, Augoff K. The Effect of Neddylation Inhibition on Inflammation-Induced MMP9 Gene Expression in Esophageal Squamous Cell Carcinoma. Int J Mol Sci. 2021;22: pubmed publisher
product information
Product Type :
Antibody
Product Name :
MMP14 Polyclonal Antibody
Catalog # :
PA5-13183
Quantity :
400 uL
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography, Protein A
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:25, Western Blot: 1:2,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
Immunogen :
KLH conjugated synthetic peptide between 145-174 amino acids from the N-terminal region of human MMP14
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:25, Western Blot: 1:2,000
Aliases :
AI325305; cb386; EC 3.4.24.80; matrix metallo protease; matrix metallopeptidase 14; matrix metallopeptidase 14 (membrane-inserted); matrix metallopeptidase 14a (membrane-inserted); matrix metalloproteinase 14 (membrane-inserted); matrix metalloproteinase 14 (membrane-inserted) alpha; matrix metalloproteinase 14 membrane-inserted; matrix metalloproteinase 14, membrane-inserted; matrix metalloproteinase 14a (membrane-inserted); matrix metalloproteinase-14; matrix metalloproteinase-14a; membrane type 1 metalloprotease; membrane type 1-matrix metalloproteinase; Membrane type 1-MMP; membrane-type matrix metalloproteinase 1; membrane-type matrix metalloproteinase 1 alpha; membrane-type-1 matrix metalloproteinase; MMP; MMP14; MMP-14; mmp14a; MMPs; MMP-X MT-MMP; MMP-X1; MT1MMP; MT1-MMP; MT1-MMP-alpha; Mtmmp; MT-MMP; MT-MMP 1; MT-MMP MT1-MMP; MTMMP1; MT-MMP-1; MT-MMPalpha; sabe; sb:cb386; type 1 matrix metalloprotease 14; WNCHRS; wu:fb72b09; zMT-MMPalpha; zMT-MMP-alpha
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA