This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Phospho-PAK1 (Thr423) Polyclonal Antibody
catalog :
PA5-12844
quantity :
400 uL
price :
US 474.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human
application :
western blot, immunocytochemistry, dot blot
citations: 2
Reference
Laine S, Högel H, Ishizu T, Toivanen J, Yli Karjanmaa M, Gronroos T, et al. Effects of Different Exercise Training Protocols on Gene Expression of Rac1 and PAK1 in Healthy Rat Fast- and Slow-Type Muscles. Front Physiol. 2020;11:584661 pubmed publisher
Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Phospho-PAK1 (Thr423) Polyclonal Antibody
Catalog # :
PA5-12844
Quantity :
400 uL
Price :
US 474.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography, Protein A
Host :
Rabbit
Reactivity :
Human
Applications :
Dot Blot: 1:500, Immunocytochemistry: 1:10-1:50, Western Blot: 1:500
Species :
Human
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
PAK1 is a serine/threonine kinase that is a target for restenosis, cancer, and immunosuppression treatment. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology.
Immunogen :
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T423 of human PAK1
Format :
Liquid
Applications w/Dilutions :
Dot Blot: 1:500, Immunocytochemistry: 1:10-1:50, Western Blot: 1:500
Aliases :
activated protein kinase alpha; ADRB2; adriamycin resistance-associated; alpha pak; alpha-PAK; ARA; AW045634; Beta-PAK; bPAK; CDC42/RAC effector kinase PAK-A; C-t-PAK2; EC 2.7.11.1; gamma-PAK; kinase PAK1; MGC130000; MGC130001; MRX30; MRX47; Oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 1; p21 (CDKN1A)-activated kinase 2; p21 (CDKN1A)-activated kinase 3; p21 (RAC1) activated kinase 1; p21 (RAC1) activated kinase 2; p21 (RAC1) activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 1; p21 protein (Cdc42/Rac)-activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 3; p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast); p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related); p21-activated kinase 1; p21-activated kinase 2; p21-activated kinase 3; p27; p34; p58; p65-PAK; p68-PAK; PAK 1; PAK1; PAK-1; PAK1B; PAK2; PAK-2; PAK-2p27; PAK-2p34; PAK3; PAK-3; PAK3beta; PAK65; Paka; PAKalpha; PAKgamma; protein kinase MUK2; S6/H4 kinase; serine/threonine-protein kinase PAK 1; Serine/threonine-protein kinase PAK 2; serine/threonine-protein kinase PAK 3; STE20 homolog, yeast
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA