Pepsin Polyclonal Antibody | Invitrogen PA5-121696 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Pepsin Polyclonal Antibody

catalog :

PA5-121696

quantity :

20 uL

price :

US 151.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

Pepsin Polyclonal Antibody

Catalog # :

PA5-121696

Quantity :

20 uL

Price :

US 151.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 5-20 ug/mL, Immunohistochemistry (Paraffin): 5-20 ug/mL, Western Blot: 0.5-2 ug/mL

Species :

Human

Isotype :

IgG

Storage :

-20 C

Description :

PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity (pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.

Immunogen :

Recombinant protein Pepsin

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5-20 ug/mL, Immunohistochemistry (Paraffin): 5-20 ug/mL, Western Blot: 0.5-2 ug/mL

Aliases :

1110035E17Rik; Pepf; pepsin A; pepsin A-5; Pepsin F; Pepsinogen 5; pepsinogen 5, group I; pepsinogen 5, group I (pepsinogen A); pepsinogen A; pepsinogen A precursor; pepsinogen A5; pepsinogen F; pepsinogen F protein; pepsinogen precursor; pepsinogen-5; Pg5; PGA; PGA3; PGA4; PGA5