This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
APAF1 Polyclonal Antibody
catalog :
PA5-120054
quantity :
100 uL
price :
US 460.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry
product information
Product Type :
Antibody
Product Name :
APAF1 Polyclonal Antibody
Catalog # :
PA5-120054
Quantity :
100 uL
Price :
US 460.00
Clonality :
Polyclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Western Blot: 1:500-1:1,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
APAF1 gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
Immunogen :
Recombinant fusion protein containing a sequence corresponding to amino acids 470-600 of human APAF1 (NP_863651.1).
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Western Blot: 1:500-1:1,000
Aliases :
6230400I06Rik; APAF1; APAF-1; Apaf1l; apoptotic peptidase activating factor 1; apoptotic protease activating factor 1; apoptotic protease-activating factor 1; CED4; DKFZp781B1145; fog; forebrain overgrowth; KIAA0413; mKIAA0413
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA