This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SKI Polyclonal Antibody
catalog :
PA5-119873
quantity :
100 uL
price :
US 460.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
SKI Polyclonal Antibody
Catalog # :
PA5-119873
Quantity :
100 uL
Price :
US 460.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunohistochemistry (Paraffin): 1:100-1:500, Western Blot: 1:500-1:1,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Ski functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes. Ski will also bind to the Smad proteins specific to bone morphogenic proteins (BMPs) and block BMP signaling in mammalian cells.
Immunogen :
Recombinant protein within human SKI aa 250-450
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:100-1:500, Western Blot: 1:500-1:1,000
Aliases :
2310012I02Rik; 2610001A11Rik; AA062172; AA589460; BC004088; C-ski; Proto-oncogene c-Ski; RGD1565591; SGS; SKI; Ski oncogene; ski oncoprotein; SKI proto-oncogene; ski sarcoma viral oncogene homolog; ski sarcoma viral oncogene homolog (avian); SKV; Sloan-Kettering viral oncogene homolog; v-ski avian sarcoma viral oncogene homolog
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA