Saccharomyces cerevisiae ZIP1 Polyclonal Antibody | Invitrogen PA5-117585 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Saccharomyces cerevisiae ZIP1 Polyclonal Antibody

catalog :

PA5-117585

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Saccharomyces cerevisiae S288C

application :

western blot

product information

Product Type :

Antibody

Product Name :

Saccharomyces cerevisiae ZIP1 Polyclonal Antibody

Catalog # :

PA5-117585

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Protein G

Host :

Rabbit

Reactivity :

Yeast

Applications :

Western Blot: 1:1,000-1:5,000

Species :

Yeast

Isotype :

IgG

Storage :

-20 C or -80 C if preferred

Description :

ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer. More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-kappa-B, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.

Immunogen :

Recombinant Saccharomyces cerevisiae Synaptonemal complex protein ZIP1 protein (1-227aa)

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000-1:5,000

Aliases :

CGI-08; CGI-71; IRT1; mZIP1; SLC39A1; solute carrier family 39 (zinc transporter), member 1; solute carrier family 39 (zinc transporter), member 3; solute carrier family 39 member 1; Zinc transporter ZIP1; Zinc-iron-regulated transporter-like; Zip1; ZIP-1; ZIRTL; Zrt- and Irt-like protein 1; Zrt/Irt-like protein 1