Phospho-LRP6 (Ser1490) Polyclonal Antibody | Invitrogen PA5-117266 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-LRP6 (Ser1490) Polyclonal Antibody

catalog :

PA5-117266

quantity :

100 uL

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

product information

Product Type :

Antibody

Product Name :

Phospho-LRP6 (Ser1490) Polyclonal Antibody

Catalog # :

PA5-117266

Quantity :

100 uL

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

ELISA: 1 ug/mL, Western Blot: 1:100-1:500

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.

Immunogen :

A synthetic phosphorylated peptide around S1490 of human LRP6 (NP_0023272)

Format :

Liquid

Applications w/Dilutions :

ELISA: 1 ug/mL, Western Blot: 1:100-1:500

Aliases :

ADCAD2; C030016K15Rik; Cd; crooked; FLJ90062; FLJ90421; Gw; LDL receptor related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein receptor-related protein 6; low density lipoprotein-related protein 6; low density lipoprotein-related protein 6; low-density lipoprotein receptor-related protein 6; lpr6; LRP6; LRP-6; ska ; ska26; skax26; STHAG7