This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PDE12 Polyclonal Antibody
catalog :
PA5-116741
quantity :
100 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, ELISA, immunocytochemistry
product information
Product Type :
Antibody
Product Name :
PDE12 Polyclonal Antibody
Catalog # :
PA5-116741
Quantity :
100 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Mouse, Rat
Applications :
ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Western Blot: 1:500-1:2,000
Species :
Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
PDE12 is an enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. It also cleaves 3',5'-phosphodiester bond of oligoadenylates and plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.
Immunogen :
Recombinant fusion protein containing a sequence corresponding to amino acids 17-300 of human PDE12 (NP_0013091061)
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Western Blot: 1:500-1:2,000
Aliases :
2',5'-phosphodiesterase 12; 2',5'-phosphodiesterase 12-like protein; 2'-PDE; 2-PDE; 2'-phosphodiesterase; E430028B21Rik; fc58c05; fi42f03; LOC558284 protein; LOW QUALITY PROTEIN: 2',5'-phosphodiesterase 12; LRRGT00074; Mitochondrial deadenylase; PDE12; phosphodiesterase 12; RGD1310975; wu:fc58c05; wu:fi42f03; zgc:136374
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA