GZMB/GZMH Polyclonal Antibody | Invitrogen PA5-115323 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GZMB/GZMH Polyclonal Antibody

catalog :

PA5-115323

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

GZMB/GZMH Polyclonal Antibody

Catalog # :

PA5-115323

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

GZMB/GZMH are members of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

Immunogen :

A synthesized peptide derived from human GZMB(Accession P10144), corresponding to amino acid residues M1-G50.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:3,000

Aliases :

AI553453; C11; cathepsin G-like 1; Cathepsin G-like 2; cathepsin G-like 2, protein h-CCPX; CCP1; CCP-1/C11; CCPI; CCP-X; CGL1; CGL-1; CGL2; CGL-2; CSPB; CSP-B; CSP-C; CTLA1; CTLA-1; CTSGL1; CTSGL2; Cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic serine protease C; Cytotoxic T-lymphocyte proteinase; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; cytotoxin serine protease-C; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme H; granzyme H (cathepsin G-like 2, protein h-CCPX); Granzyme-2; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; GZMB; GZMH; GZMH/GZMB; HLP; human lymphocyte protein; Lymphocyte protease; Natural killer cell protease 1; RNKP-1; SECT; T-cell serine protease 1-3E