APOBEC3B Polyclonal Antibody | Invitrogen PA5-11430 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

APOBEC3B Polyclonal Antibody

catalog :

PA5-11430

quantity :

400 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

citations: 2

Reference
Evgin L, Huff A, Kottke T, Thompson J, Molan A, Driscoll C, et al. Suboptimal T-cell Therapy Drives a Tumor Cell Mutator Phenotype That Promotes Escape from First-Line Treatment. Cancer Immunol Res. 2019;7:828-840 pubmed publisher
Huff A, Wongthida P, Kottke T, Thompson J, Driscoll C, Schuelke M, et al. APOBEC3 Mediates Resistance to Oncolytic Viral Therapy. Mol Ther Oncolytics. 2018;11:1-13 pubmed publisher

product information

Product Type :

Antibody

Product Name :

APOBEC3B Polyclonal Antibody

Catalog # :

PA5-11430

Quantity :

400 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen :

KLH conjugated synthetic peptide between 299-330 amino acids from the C-terminal region of human APOBEC3B (PHO3)

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

A3B; A3Z2_1; A3Z2-Z3; A3Z3; A3Z3_1; APOBEC1L; Apobec3; Apobec3b; Apobec3f; APOBEC3F1; APOBEC3F2; APOBEC3Z2; APOBEC3Z3; apolipoprotein B editing complex 3; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3B; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B; apolipoprotein B mRNA editing enzyme catalytic subunit 3B; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F; apolipoprotein B mRNA-editing complex 3; ARCD3; Arp3; ARP4; BC003314; bK150C 2.2; bK150C2.2; Cem15; CEM-15; cytidine deaminase; DJ742C19.2; DNA dC->dU-editing enzyme APOBEC3; DNA dC->dU-editing enzyme APOBEC-3; DNA dC->dU-editing enzyme APOBEC-3B; FLJ21201; phorbolin 2; phorbolin 3; phorbolin-1-related protein; Phorbolin-2/3; PHRBNL; probable DNA dC->dU-editing enzyme APOBEC3; probable DNA dC->dU-editing enzyme APOBEC-3B; recovery from Friend virus 3; Rfv3