Bax Polyclonal Antibody | Invitrogen PA5-11378 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Bax Polyclonal Antibody

catalog :

PA5-11378

quantity :

400 uL

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, flow cytometry

citations: 10

Reference
Li J, Bai J, Tuerdi N, Liu K. Long non-coding RNA MEG3 promotes tumor necrosis factor-alpha induced oxidative stress and apoptosis in interstitial cells of cajal via targeting the microRNA-21 /I-kappa-B-kinase beta axis. Bioengineered. 2022;13:8676-8688 pubmed publisher
Abdelrahman R, Abdelsalam R, Zaghloul M. Beneficial effect of trimetazidine on folic acid-induced acute kidney injury in mice: Role of HIF-1α/HO-1. J Biochem Mol Toxicol. 2022;36:e23011 pubmed publisher
Feng C, Wang Q, Deng L, Peng N, Yang M, Wang X. Hsa_circ_0074032 promotes prostate cancer progression through elevating homeobox A1 expression by serving as a microRNA-198 decoy. Andrologia. 2022;54:e14312 pubmed publisher
Zhang H, Wu G, Feng J, Lu X, Liu P. Expression of STOML2 promotes proliferation and glycolysis of multiple myeloma cells via upregulating PAI-1. J Orthop Surg Res. 2021;16:667 pubmed publisher
Venturini G, Kokona D, Steiner B, Bulla E, Jovanovic J, Zinkernagel M, et al. In vivo analysis of onset and progression of retinal degeneration in the Nr2e3rd7/rd7 mouse model of enhanced S-cone sensitivity syndrome. Sci Rep. 2021;11:19032 pubmed publisher
Hu X, Lou T, Yuan C, Wang Y, Tu X, Wang Y, et al. Effects of lncRNA ANRIL-knockdown on the proliferation, apoptosis and cell cycle of gastric cancer cells. Oncol Lett. 2021;22:621 pubmed publisher
Ezzat D, Soliman A, El Kashef D. Nicorandil mitigates folic acid-induced nephrotoxicity in mice: Role of iNOS and eNOS. J Biochem Mol Toxicol. 2021;35:e22692 pubmed publisher
Habib S, Abdelrahman R, Abdel Rahim M, Suddek G. Anti-apoptotic effect of vinpocetine on cisplatin-induced hepatotoxicity in mice: The role of Annexin-V, Caspase-3, and Bax. J Biochem Mol Toxicol. 2020;34:e22555 pubmed publisher
Mao Y, Tie Y, Du J, He J. LINC00152 promotes the proliferation of gastric cancer cells by regulating B-cell lymphoma-2. J Cell Biochem. 2019;120:3747-3756 pubmed publisher
Zheng P, Wang W, Ji M, Zhu Q, Feng Y, Zhou F, et al. TMEM119 silencing inhibits cell viability and causes the apoptosis of gastric cancer SGC-7901 cells. Oncol Lett. 2018;15:8281-8286 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Bax Polyclonal Antibody

Catalog # :

PA5-11378

Quantity :

400 uL

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography, Protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Flow Cytometry: 1:25, Western Blot: 1:2,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

BAX is a members of the Bcl-2 Family and plays an important role in regulation of apoptosis. Whereas Bcl-2 is commonly regarded as an anti-apoptotic protein, BAX is considered to have a pro-apoptotic function. Regulation of apoptosis is supposed to involve both homo- and heterodimerization of different isoforms of BAX and Bcl-2. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa), whereas both isoforms contain the BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. Bcl-2 is also expressed in different Isoforms. Bcl-2 beta differs in the 3' UTR and coding region compared to variant alpha. Bcl-2 beta is shorter (22 kDa) and has a distinct C-terminus compared to Bcl-2 alpha (26 kDa). BAX is a member of the BCL-2 family of proteins, which function as regulators of apoptosis. Overexpression of BAX functions to promote cell death. BAX can form homodimers and is also able to heterodimerize with other BCL-2 related proteins.

Immunogen :

KLH conjugated synthetic peptide between 41-76 amino acids from human Bax

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:25, Western Blot: 1:2,000

Aliases :

apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52