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company name :
Invitrogen
other brands :
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product type :
antibody
product name :
SUV39H2 Polyclonal Antibody
catalog :
PA5-11366
quantity :
400 µL
price :
US 470
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig s20b
Nicetto D, Donahue G, Jain T, Peng T, Sidoli S, Sheng L, et al. H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science. 2019;363:294-297 pubmed publisher
Piao L, Yuan X, Zhuang M, Qiu X, Xu X, Kong R, et al. Histone methyltransferase SUV39H2 serves oncogenic roles in osteosarcoma. Oncol Rep. 2019;41:325-332 pubmed publisher
image
image 1 :
Invitrogen PA5-11366 image 1
image 2 :
Invitrogen PA5-11366 image 2
image 3 :
Invitrogen PA5-11366 image 3
product information
Product Type :
Antibody
Product Name :
SUV39H2 Polyclonal Antibody
Catalog # :
PA5-11366
Quantity :
400 µL
Price :
US 470
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation
Host :
Rabbit
Reactivity :
Human, Rat
Applications :
Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000
Species :
Human, Rat
Isotype :
IgG
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59% identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.
Immunogen :
KLH conjugated synthetic peptide between 360-390 amino acids from the C-terminal region of human SUV39H2
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1,000
Aliases :
4930507K23Rik; AA536750; D030054H19Rik; D2Ertd544e; FLJ23414; H3 K9 HMTase 2; H3-K9-HMTase 2; Histone H3-K9 methyltransferase 2; histone-lysine N-methyltransferase SUV39H2; KMT1; KMT1B; lysine N-methyltransferase 1B; RP11-2K17.2; Su; Su(var)3-9 homolog 2; suppressor of variegation 3-9 homolog 2; suppressor of variegation 3-9 homolog 2 (Drosophila); Suv39h histone methyltransferase; Suv39h2
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA