This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SMO Polyclonal Antibody
catalog :
PA5-113312
quantity :
100 ug
price :
US 424.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
SMO Polyclonal Antibody
Catalog # :
PA5-113312
Quantity :
100 ug
Price :
US 424.00
Clonality :
Polyclonal
Purity :
Protein G
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
ELISA: Assay-dependent, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1,000-1:5,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C or -80 C if preferred
Description :
Smoothened drosophila homolog (SMOH) is a serpentine protein belonging to the G-protein coupled receptor Fz/Smo family with 787 aa, seven transmembrane G protein-coupled receptors with 4 glycosylation sites and a putative extracellular amino terminus. Smoothened activated by b-Arrestin 2 and GRK2 acts as a receptor for Shh, the Sonic hedgehog gene product, and is a positive regulator of hedgehog signaling pathway along with the smoothened inhibitor patched protein (PTCH) and regulates vertebrate developmental processes, cellular proliferation and differentiation by activating transcription factor Gli. Smoothened mutants are known to cause sporadic basal cell carcinoma of the skin. It is known to express widely in heart and brain.
Immunogen :
Recombinant Human Smoothened homolog protein (28-233AA)
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunocytochemistry: 1:50-1:200, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1,000-1:5,000
Aliases :
bent body; bnb; E130215L21Rik; frizzled family member 11; FZD11; Gx; HGNC:11119; Protein Gx; Protein SMOH; seven transmembrane helix receptor; SMO; SMOH; smoothened; Smoothened homolog; smoothened homolog (Drosophila); smoothened, frizzled class receptor; smoothened, frizzled family receptor; smoothened, seven transmembrane spanning receptor
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA