This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MEP1B Polyclonal Antibody
catalog :
PA5-112908
quantity :
100 uL
price :
US 430.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
MEP1B Polyclonal Antibody
Catalog # :
PA5-112908
Quantity :
100 uL
Price :
US 430.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
ELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1,000-1:5,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C or -80 C if preferred
Description :
Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.
Immunogen :
Recombinant Human Meprin A subunit beta protein (480-652AA)
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Immunohistochemistry (Paraffin): 1:20-1:200, Western Blot: 1:1,000-1:5,000
Aliases :
EC 3.4.24.63; Endopeptidase-2; MEP1B; Mep-1b; meprin 1 beta; meprin A; meprin A subunit beta; meprin A, beta; meprin B; meprin beta; N-benzoyl-L-tyrosyl-p-amino-benzoic acid hydrolase beta subunit; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta; PABA peptide hydrolase; PPH beta
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA