RHD Polyclonal Antibody | Invitrogen PA5-112694 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RHD Polyclonal Antibody

catalog :

PA5-112694

quantity :

100 ug

price :

US 424.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

RHD Polyclonal Antibody

Catalog # :

PA5-112694

Quantity :

100 ug

Price :

US 424.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography, Protein G

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 1:50-1:200, Western Blot: 1:2,000-1:5,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

-20 C or -80 C if preferred

Description :

The Rhesus (Rh) blood group system represents one of the most complex and important systems in humans. Two highly homologous genes RHD and RHCE (collectively referred to as RH30 or RHCED) encode the antigens of the Rh blood group system (1-4). These tightly linked genes map to human chromosomal position 1p34.1-1p36. The RHD gene, which is commonly deleted from a large segment of the population, encodes the most potent blood group immunogen, the D antigen (2,5). Rh incompatibility between maternal and fetal blood types results in hemolytic disease of the newborn (HDN), which often results in fetal death (1,2,6). The RHCE gene exists in four allelic forms, and each allele determines the expression of two antigens in Ce, ce, cE, or CE combinations (2,4,5). The RHCED antigens exist as integral membrane proteins with contain 12-transmembrane helices, and maintain erythrocyte membrane integrity. The presentation of the Rh antigenic activity requires the formation of a complex between the RHCED antigens and RHAG (RH50).

Immunogen :

Recombinant Human Blood group Rh(D) polypeptide protein (32-76AA)

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 1:50-1:200, Western Blot: 1:2,000-1:5,000

Aliases :

blood group antigen D; blood group protein RHD; blood group Rh(D) polypeptide; CD240D; D antigen (DCS); DIIIc; Erythrocyte membrane glycoprotein Rh30; Rh; Rh blood group antigen Evans; Rh blood group D antigen; Rh blood group protein; Rh blood group, D anitgen; Rh blood group, D antigen; RH polypeptide 2; Rh30; Rh4; Rhced; RHD; RhD blood group antigen; RhD polypeptide; RhDCw; RHDel; RHDVA(TT); Rhesus blood group CE and D; Rhesus blood group D antigen allele DIII type 7; rhesus D antigen; Rhesus system D polypeptide; RhII; RhK562-II; Rhl1; Rh-like polypeptide; RhPI; RHPII; RHXIII; truncated rhesus blood group D antigen; truncated rhesus D