This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PSEN2 Polyclonal Antibody
catalog :
PA5-112675
quantity :
100 ug
price :
US 430.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, ELISA
product information
Product Type :
Antibody
Product Name :
PSEN2 Polyclonal Antibody
Catalog # :
PA5-112675
Quantity :
100 ug
Price :
US 430.00
Clonality :
Polyclonal
Purity :
Protein G
Host :
Rabbit
Reactivity :
Human, Rat
Applications :
ELISA: Assay-dependent, Western Blot: 1:500-1:5,000
Species :
Human, Rat
Isotype :
IgG
Storage :
-20 C or -80 C if preferred
Description :
Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor such that, they either directly regulate gamma-secretase activity, or themselves act are protease enzymes. Two alternatively spliced transcript variants encoding different isoforms of PSEN2 have been identified.
Immunogen :
Recombinant Human Presenilin-2 protein (7-77AA)
Format :
Liquid
Applications w/Dilutions :
ELISA: Assay-dependent, Western Blot: 1:500-1:5,000
Aliases :
AD3L; AD3LP; AD4; Ad4h; AD5; Alg3; ALG-3; Alzheimer disease 4; CMD1V; E5-1; presenilin 2; presenilin-2; Presenilin-2 CTF subunit; Presenilin-2 NTF subunit; PS2; Ps-2; PSEN 2; PSEN2; Psnl2; STM2; STM-2
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA