This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
UCP4 Polyclonal Antibody
catalog :
PA5-110384
quantity :
100 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, ELISA, immunocytochemistry
citations: 1
Reference
Carli S, Chaabane L, Butti C, De Palma C, Aimar P, Salio C, et al. In vivo magnetic resonance spectroscopy in the brain of Cdkl5 null mice reveals a metabolic profile indicative of mitochondrial dysfunctions. J Neurochem. 2021;157:1253-1269 pubmed publisher
product information
Product Type :
Antibody
Product Name :
UCP4 Polyclonal Antibody
Catalog # :
PA5-110384
Quantity :
100 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Affinity Chromatography
Host :
Rabbit
Reactivity :
Mouse, Rat
Applications :
ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Western Blot: 1:500-1:2,000
Species :
Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
UCP4 is a 323 amino acid mitochondrial uncoupling protein belonging to the large mitochondrial substrate carrier family with three Solcar repeats. UCP4 is a mitochondrial transport carrier that facilitates the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. It reduces the mitochondrial membrane potential in mammalian cells and is involved in thermoregulatory heat production. UCP4 creates proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis resulting in dissipation of energy in the form of heat. UCP4 is usually found in adult and fetal brain, with low levels in spinal chord, corpus callosum and substantia nigra.
Immunogen :
Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human SLC25A27 (NP_001190981.1).
Format :
Liquid
Applications w/Dilutions :
ELISA: 1 ug/mL, Immunocytochemistry: 1:50-1:200, Western Blot: 1:500-1:2,000
Aliases :
3632410G24Rik; 9430092A03Rik; D530043E16Rik; Mitochondrial uncoupling protein 4; slc25a27; Solute carrier family 25 member 27; solute carrier family 25, member 27; UCP 4; ucp4; uncoupling protein; uncoupling protein 4; uncoupling protein UCP-4; UNQ772/PRO1566; zgc:63899
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA