BLOS1 Polyclonal Antibody | Invitrogen PA5-109347 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

BLOS1 Polyclonal Antibody

catalog :

PA5-109347

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

thale cress

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

BLOS1 Polyclonal Antibody

Catalog # :

PA5-109347

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Plant

Applications :

Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:500-1:2,000

Species :

Plant

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles, store in dark

Description :

Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that mediates the vacuolar degradative transport via the intracellular vesicle trafficking from the endosome to the vacuole. Probably regulates the PIN1 and PIN2 homeostasis through its interaction with SNX1. An eight-subunit protein complex, BLOC-1, which is involved in endosomal transport from the endosomes to the lysosomes, has been identified in both human and mice. In this study, two homologous subunits of this complex, BLOS1 (or AtGCN5L1) and BLOS2, have been characterized in Arabidopsis. Both BLOS1 and BLOS2 interacted with SNX1 on the sorting endosomes. Inducible RNAi lines with reduced levels of BLOS1 had longer primary roots and more lateral roots. Consistently, PIN1 and PIN2 were increased in BLOS1 RNAi lines, implicating an impaired transport from the endosomes to the vacuoles. These results suggest that a putative BLOC-1 complex in Arabidopsis might mediate the vacuolar degradative transport through direct interaction with SNX1 to regulate the homeostasis of PIN1 and PIN2, which is important for plant growth and development.

Immunogen :

Synthetic peptide within thaliana BLOS1 aa 26-75

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50, Western Blot: 1:500-1:2,000

Aliases :

At2g30330; Biogenesis of lysosome-related organelles complex 1 subunit 1; BLOC subunit 1; BLOC-1 subunit 1; BLOS1; GCN5L1; GCN5L1 family protein; GCN5-like protein 1; Protein RT14 homolog; T09D09.14; T9D9.14; T9D9_14; unknown protein