This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Ryanodine Receptor Polyclonal Antibody
catalog :
PA5-109278
quantity :
100 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, dot blot
product information
Product Type :
Antibody
Product Name :
Ryanodine Receptor Polyclonal Antibody
Catalog # :
PA5-109278
Quantity :
100 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Dot Blot: 1:500, Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:50-1:100, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500
Species :
Human
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles, store in dark
Description :
The ryanodine receptor (RyR) is the channel responsible for the release of calcium from the sarcoplasmic reticulum (SR) in muscle cells and also plays a role in calcium regulation in non-muscle cells. The RyR exists as a homotetramer and is predicted to have a short cytoplasmic C-terminus and 4-10 transmembrane domains; the remainder of the protein, termed the 'foot' region is located in the cytoplasm between the T-tubule and the SR. The mammalian RyR is the product of three different genes: RyR-1, which is expressed predominantly in skeletal muscle and areas of the brain, RyR-2, which is expressed predominantly in the heart muscle but also found in the stomach, endothelial cells and diffuse areas of the brain, and RyR-3 which is found in smooth muscle and the brain (striatum, thalamus and hippocampus).
Immunogen :
Synthetic peptide within Human RYR2 aa 1,471-1,520
Format :
Liquid
Applications w/Dilutions :
Dot Blot: 1:500, Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:50-1:100, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500
Aliases :
9330127I20Rik; AI528790; ARVC2; ARVD2; Ca2+ release channel; calcium release channel; cardiac muscle ryanodine receptor; Cardiac muscle ryanodine receptor-calcium release channel; cardiac muscle-type ryanodine receptor; cardiac ryanodine receptor; cardiac ryanodine receptor 2; cardiac-type ryanodine receptor; CCO; central core disease of muscle; islet-type ryanodine receptor; kidney-type ryanodine receptor; LOW QUALITY PROTEIN: ryanodine receptor 1; MHS; MHS1; PPP1R137; protein phosphatase 1, regulatory subunit 137; ryanodine receptor; ryanodine receptor 1; ryanodine receptor 1 (skeletal); ryanodine receptor 1, skeletal muscle; ryanodine receptor 1-like, skeletal muscle; ryanodine receptor 2; ryanodine receptor 2 (cardiac); ryanodine receptor 2, cardiac; ryanodine receptor type 2; ryanodine receptor type II; RYDR; Ryr; RYR1; RYR-1; Ryr1l; Ryr2; RYR-2; sarcoplasmic reticulum calcium release channel; skeletal muscle calcium release channel; Skeletal muscle ryanodine receptor; skeletal muscle-type ryanodine receptor; SKRR; Type 1 ryanodine receptor; type 1-like ryanodine receptor; type 2 ryanodine receptor; unnamed protein product; VTSIP
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA