SLC9A7 Polyclonal Antibody | Invitrogen PA5-106748 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SLC9A7 Polyclonal Antibody

catalog :

PA5-106748

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

SLC9A7 Polyclonal Antibody

Catalog # :

PA5-106748

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:500-1:1,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

Na+/H+ exchangers (NHE) of mammalian cells are plasma membrane intrinsic proteins mediating exchange of N+ and H+ ions in various tissues. The NHE catalyzes the electroneural transport of extracellular Na+ for intracellular H+. They play a major role in regulation of intracellular pH (pHi) in addition to trans-cellular absorption of Na+, cell volume regulation and possibly in cell proliferation. These primary functions of the Na+/H+ exchanger have been related to many pathophysiological states, include hypertension, organ growth and hypertrophy, regression of cancer and renal intestinal disorders. At least 7 NHE isoforms (NHE1-7) have been cloned so far. They are all similar in their primary structure and predicted to have 10-12 transmembrane domains. The C-terminal domain of NHEs are predicted to be intracellular. NHE7 (human 725 aa, chromosome Xp11.4) is ubiquitously expressed, and predominantly localizes to the trans-golgi network. NHE7 mediates the influx of Na+ or K+ in exchange for H+. It is ~70% related to NHE6 but relatively less (~25%) homologous with other NHEs.

Immunogen :

A synthesized peptide derived from human SLC9A7(Accession Q96T83), corresponding to amino acid residues L535-A585.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:500-1:1,000

Aliases :

A530087D17Rik; hypothetical protein LOC554532; Na(+)/H(+) exchanger 7; Nhe7; NHE-7; nonselective sodium potassium/proton exchanger; SLC9A6; Slc9a7; Sodium/hydrogen exchanger 7; solute carrier family 9 (sodium/hydrogen exchanger), isoform 7; solute carrier family 9 (sodium/hydrogen exchanger), member 7; solute carrier family 9 member 7; solute carrier family 9 member A7; solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7; wu:fk03b09; zgc:101088; zgc:113878