Phospho-MARK Pan (Thr215) Polyclonal Antibody | Invitrogen PA5-105814 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-MARK Pan (Thr215) Polyclonal Antibody

catalog :

PA5-105814

quantity :

100 uL

price :

US 450.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

Phospho-MARK Pan (Thr215) Polyclonal Antibody

Catalog # :

PA5-105814

Quantity :

100 uL

Price :

US 450.00

Clonality :

Polyclonal

Purity :

sequential chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:1,000-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

MARK1 (MAP/microtubule affinity-regulating kinase 1) belongs to the MARK family of serine/threonine kinases. MARK family protein kinases phosphorylate microtubule-associated proteins and may play a role in cytoskeletal stability. MARK2 refers to MAP/microtubule affinity-regulating kinase 2 isoform a [Homo sapiens]. EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1 called MARK2. MARK3 was originally identified as a marker that was induced by treatment with DNA damaging agents, and loss of MARK3 was found with carcinogenesis in the pancreas. MARK4 contains an N terminal serine/threonine kinase domain, a central ubiquitin associated domain, and a C terminal KA1 associated kinase domain. RT PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells.

Immunogen :

A synthesized peptide derived from human MARK1(Accession Q9P0L2), corresponding to amino acid residues around phosphorylated Thr215.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:1,000-1:3,000

Aliases :

1600015G02Rik; 2410090P21Rik; A430080F22Rik; AW491150; B930025N23Rik; C79806; Cdc25C-associated protein kinase 1; cTAK1; C-TAK1; ELKL motif kinase 1; ELKL motif kinase 2; ELKL motif serine/threonine-protein kinase 3; ELKL motif serine-threonine protein kinase 3; Emk; EMK1; EMK-1; Emk2; EMK-2; EMK2/MARK3 serine-threonine protein kinase; Emk3; ETK1; ETK-1; KIAA1477; Kiaa1860; KP78; MAP/microtubule affinity regulating kinase 1; MAP/microtubule affinity regulating kinase 2; MAP/microtubule affinity regulating kinase 3; MAP/microtubule affinity regulating kinase 4; MAP/microtubule affinity-regulating kinase 1; MAP/microtubule affinity-regulating kinase 2; MAP/microtubule affinity-regulating kinase 3; MAP/microtubule affinity-regulating kinase 4; MAP/microtubule affinity-regulating kinase 4L; MAP/microtubule affinity-regulating kinase like 1; MAP/microtubule affinity-regulating kinase-like 1; MARK; MARK1; mark1 {ECO:0000312; MARK2; mark2 {ECO:0000312; MARK3; MARK4; MARK4 serine/threonine protein kinase; MARK4L; MARK4S; MARKL1; MARKL1L; microtubule affinity regulating kinase 1; microtubule affinity regulating kinase 2; microtubule affinity regulating kinase 3; microtubule affinity regulating kinase 4; mKIAA1477; mPar-1c; MPK10; MPK-10; Par-1; PAR1 homolog; PAR1 homolog b; PAR1 homolog c; PAR1A; Par-1a; Par1b; Par-1b; Par1c; Par-1c; PAR-1D; protein kinase STK10; RGD:619882}; RGD:708483}; Ser/Thr protein kinase PAR-1; Ser/Thr protein kinase PAR-1B; serine/threonine kinase; serine/threonine protein kinase EMK; serine/threonine-protein kinase MARK1; Serine/threonine-protein kinase MARK2; serine/threonine-protein kinase p78; testicular tissue protein Li 117