DCT Polyclonal Antibody | Invitrogen PA5-105275 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DCT Polyclonal Antibody

catalog :

PA5-105275

quantity :

100 uL

price :

US 486.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Li X, Shi R, Yan L, Chu W, Sun R, Zheng B, et al. Natural product rhynchophylline prevents stress-induced hair graying by preserving melanocyte stem cells via the β2 adrenergic pathway suppression. Nat Prod Bioprospect. 2023;13:54 pubmed publisher

product information

Product Type :

Antibody

Product Name :

DCT Polyclonal Antibody

Catalog # :

PA5-105275

Quantity :

100 uL

Price :

US 486.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.

Immunogen :

A synthesized peptide derived from human DCT(Accession P40126), corresponding to amino acid residues Q56-C106.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000

Aliases :

Dct; DOPAchrome conversion factor; dopachrome delta isomerase; dopachrome delta-isomerase; DOPAchrome isomerase; DOPAchrome oxidoreductase; dopachrome tautomerase; dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2); DT; hypothetical protein LOC664745; L-dopachrome Delta-isomerase; L-dopachrome isomerase; L-dopachrome tautomerase; melanogenic enzyme; tyrosinase-related protein 2; trp2; RGD1564975; slaty; SLATY locus protein; slt; trp2; TRP-2; tyrosinase related protein 2; tyrosinase related protein-2; tyrosinase-related protein 2; tyrosinase-related protein-2; tyrosine-related protein 2; Tyrp2; Tyrp-2; zgc:109860