Phospho-MYL2 (Ser15) Polyclonal Antibody | Invitrogen PA5-104265 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-MYL2 (Ser15) Polyclonal Antibody

catalog :

PA5-104265

quantity :

100 uL

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig s7b	Dufour C, Xia H, B chir W, Perry M, Kuzmanov U, Gainullina A, et al. Integrated multi-omics analysis of adverse cardiac remodeling and metabolic inflexibility upon ErbB2 and ERRα deficiency. Commun Biol. 2022;5:955 pubmed publisher
	Hu T, Kalyanaraman H, Pilz R, Casteel D. Phosphatase regulatory subunit MYPT2 knockout partially compensates for the cardiac dysfunction in mice caused by lack of myosin light chain kinase 3. J Biol Chem. 2023;299:104584 pubmed publisher
	Prasad V, Makkaoui N, Rajan R, Patel A, Mainali B, Bagchi P, et al. Loss of cardiac myosin light chain kinase contributes to contractile dysfunction in right ventricular pressure overload. Physiol Rep. 2022;10:e15238 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-MYL2 (Ser15) Polyclonal Antibody

Catalog # :

PA5-104265

Quantity :

100 uL

Price :

US 454.00

Clonality :

Polyclonal

Purity :

sequential chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:200-1:2,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

Thus gene encodes the regulatory light chain associated with cardiac myosin beta heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

Immunogen :

A synthesized peptide derived from human MYL2(Accession P10916), corresponding to amino acid residues around phosphorylated Ser15.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:200-1:2,000

Aliases :

cardiac myosin light chain 2; cardiac myosin light chain-2; cardiac ventricular myosin light chain 2; CMH10; DKFZp779C0562; hypothetical protein LOC677750; Mlc2; MLC-2; mlc2b; MLC-2s/v; MLC2V; MLC-2v; myl2; myl2b; Mylpc; myosin light chain 2; myosin light chain 2, slow skeletal/ventricular muscle isoform; myosin light chain 2V; myosin light chain phosphatase; myosin light chain, phosphorylatable, cardiac ventricles; myosin light chain-2; myosin regulatory light chain 2, ventricular/cardiac muscle isoform; myosin regulatory light chain 2b; myosin regulatory light chain ventricular isoform; myosin, light chain 2, regulatory, cardiac, slow; myosin, light chain 2b, regulatory, cardiac, slow; myosin, light polypeptide 2, regulatory, cardiac, slow; myosin, light polypeptide 2b, regulatory, cardiac, slow; regulatory light chain of myosin; RLC of myosin; slow cardiac myosin regulatory light chain 2; ventricular myosin light chain 2; ventricular myosin regulatory light chain; zgc:136848

more info or order :

Invitrogen product webpage