This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
HOXD11 Polyclonal Antibody
catalog :
PA5-103895
quantity :
100 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
product information
Product Type :
Antibody
Product Name :
HOXD11 Polyclonal Antibody
Catalog # :
PA5-103895
Quantity :
100 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Western Blot: 1:1,000-1:3,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C
Description :
HOX11, also called homeobox11 or Tcl-3 is located at the 10q24 T-Cell translocation breakpoint region. It encodes a homeobox-domain containing protein, HOX11, containing a glycine and proline-rich amino terminus. HOX11 is required for maintenance of the developing spleen and cell survival. The HOX11protein binds to a specific DNA sequence and localizes to the cell nucleus. It transactivates transcription of a reporter gene linked to a cis-regulatory element, acting as a positive transcription activator. The HOX11 gene is highly expressed in T-ALLs as a result of a t (7:10) (q35;q24) or t(10:14)(q24;qll) translocation. The homeobox gene is deregulated upon translocation into the T-cell receptor locus and activates a specific subset of tumor-associated target genes. HOX 11 gene translocation has been attributed to T-cell leukemia and lymphoid neoplasias.
Immunogen :
A synthesized peptide derived from human HOXD11(Accession P31277), corresponding to amino acid residues G206-K256.
Format :
Liquid
Applications w/Dilutions :
Western Blot: 1:1,000-1:3,000
Aliases :
E230017H14Rik; homeo box 4F; homeo box D11; homeobox D11; homeobox protein Hox-4.6; Homeobox protein Hox-4F; homeobox protein Hox-5.5; Homeobox protein Hox-D11; HOX11; HOX4; Hox-4.6; Hox-4.6, mouse, homolog of; HOX4F; Hox-5.4; Hox-5.5; Hoxd11; Hoxd-11; LOC102553842; uncharacterized LOC102553842
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA