Laminin beta-2 Polyclonal Antibody | Invitrogen PA5-103211 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Laminin beta-2 Polyclonal Antibody

catalog :

PA5-103211

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 1

Reference
Gao N, Zhao K, Cao Y, Ren X, Jing H, Xing G, et al. A Role of Lamin A/C in Preventing Neuromuscular Junction Decline in Mice. J Neurosci. 2020;40:7203-7215 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Laminin beta-2 Polyclonal Antibody

Catalog # :

PA5-103211

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:1,000-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins can be distinguished, i.e. A-type lamins and B-type lamins. The A-type lamins comprise a set of three proteins arising from the same gene by alternative splicing, i.e. lamin A, lamin C and lamin Adel 10, while the B-type lamins include two proteins arising from two distinct genes, i.e. lamin B1 and lamin B2. Recent evidence has revealed that mutations in A-type lamins give rise to a range of rare but dominant genetic disorders, including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease and Dunnigan-type familial partial lipodystrophy. In addition, the expression of A-type lamins coincides with cell differentiation and as A-type lamins specifically interact with chromatin, a role in the regulation of differential gene expression has been suggested for A-type lamins.

Immunogen :

A synthesized peptide derived from human LAMB2(Accession P55268), corresponding to amino acid residues G72-A122.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:1,000-1:3,000

Aliases :

AW211941; Lamb2; Lamb-2; Laminin B1s chain; laminin chain B3; laminin chain beta 2; Laminin S; laminin subunit beta 2; laminin subunit beta-2; laminin, beta 2; laminin, beta 2 (laminin S); laminin-11 subunit beta; Laminin-14 subunit beta; laminin-15 subunit beta; Laminin-3 subunit beta; laminin-4 subunit beta; Laminin-7 subunit beta; laminin-9 subunit beta; LAMS; NPHS5; npht; SLAM; S-LAM beta; S-laminin subunit beta