This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TAP2 Polyclonal Antibody
catalog :
PA5-102438
quantity :
100 uL
price :
US 454.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
TAP2 Polyclonal Antibody
Catalog # :
PA5-102438
Quantity :
100 uL
Price :
US 454.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C
Description :
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces two products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.
Immunogen :
A synthesized peptide derived from human TAP2(Accession Q03519), corresponding to amino acid residues E538-F588.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2,000
Aliases :
ABC transporter, MHC 2; ABC18; ABCB3; AI462429; Antigen peptide transporter 2; APT2; ATP dependent transport protein family member; ATP-binding cassette sub-family B member 3; ATP-binding cassette, sub-family B (MDR/TAP), member 3; Cim; D6S217E; Ham2; Ham-2; Histocompatibility antigen modifier 2; jas; MTP2; Peptide supply factor 2; peptide transporter involved in antigen processing 2; Peptide transporter PSF2; Peptide transporter TAP2; PSF2; PSF-2; Really interesting new gene 11 protein; RING11; TAP2; Tap-2; Transporter 2 ABC (ATP binding cassette); transporter 2 ATP-binding cassette sub-family B; transporter 2, ABC (ATP binding cassette); transporter 2, ATP binding cassette subfamily B member; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP); Y1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA