NSG1 Polyclonal Antibody | Invitrogen PA5-101719 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NSG1 Polyclonal Antibody

catalog :

PA5-101719

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

product information

Product Type :

Antibody

Product Name :

NSG1 Polyclonal Antibody

Catalog # :

PA5-101719

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:500-1:1,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C

Description :

NEEP21 (neuron-enriched endosomal 21kDa protein), also known as brain neuron cytoplasmic protein 1, NSG1 (neuron-specific proteins family member 1), P21 or D4S234E, is a single pass type II membrane protein belonging to the NSG family. It is highly expressed during neuronal maturation but its expression is downregulated in adult tissues. NEEP21 predominantly localizes to Rab 4-positive early endosomes in the somatodendritic neuronal compartment and is essential for proper receptor sorting and recycling in neurons. It associates with GRIP1 and GluR-2 and mediates the surface expression of GluR-2. When this interaction is interrupted, GluR-2 accumulates in early endosomes and leads to changes in evoked synaptic current properties. In addition, NEEP21 forms a complex with the SNARE protein, Syntaxin 13 (also known as Syntaxin 12), and participates in the recycling of transferrin receptors (TFRs) and NTR2 (Neurotensin receptor 2).

Immunogen :

A synthesized peptide derived from human NSG1(Accession P42857), corresponding to amino acid residues A111-V161.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:500-1:1,000

Aliases :

brain neuron cytoplasmic protein 1; brain neuron cytoplasmic protein 1/2; brain specific mRNA b; Bsmrb; carboxyterminally EE-tagged neuron-enriched endosomal 21 kDa protein; D4S234; D4S234E; m234; Neep21; neuron specific gene family member 1; Neuronal vesicle trafficking-associated protein 1; Neuron-enriched endosomal protein of 21 kDa; Neuron-specific protein family member 1; NSG1; p21; PEP1