This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
AKAP13 Polyclonal Antibody
catalog :
PA5-101150
quantity :
100 uL
price :
US 460.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
AKAP13 Polyclonal Antibody
Catalog # :
PA5-101150
Quantity :
100 uL
Price :
US 460.00
Clonality :
Polyclonal
Purity :
Affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
-20 C
Description :
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addition, enhance ligand-dependent activity of estrogen receptors alpha and beta.
Immunogen :
A synthesized peptide derived from human AKAP13(Accession Q12802), corresponding to amino acid residues T718-K768.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:1,000
Aliases :
1700026G02Rik; 5730522G15Rik; 5830460E08Rik; A kinase (PRKA) anchor protein 13; AKAP13; AKAP-13; AKAP-Lbc; A-kinase anchor protein 13; A-kinase anchoring protein; A-kinase anchoring protein 13; ARHGEF13; Breast cancer nuclear receptor-binding auxiliary protein; Brx; c-lbc; guanine nucleotide exchange factor Lbc; HA-3; Ht31; Human thyroid-anchoring protein 31; LBC; LBC oncogene; lymphoid blast crisis oncogene; Non-oncogenic Rho GTPase-specific GTP exchange factor; p47; PRKA13; Protein kinase A-anchoring protein 13; PROTO-LB; PROTO-LBC; type II cAMP-dependent protein kinase anchoring protein Ht31
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA