Phospho-53BP1 (Ser25, Ser29) Polyclonal Antibody | Invitrogen PA5-101035 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Phospho-53BP1 (Ser25, Ser29) Polyclonal Antibody

catalog :

PA5-101035

quantity :

100 uL

price :

US 414.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry

citations: 1

Reference
Bleiler M, Cyr A, Wright D, Giardina C. Incorporation of 53BP1 into phase-separated bodies in cancer cells during aberrant mitosis. J Cell Sci. 2023;136: pubmed publisher

product information

Product Type :

Antibody

Product Name :

Phospho-53BP1 (Ser25, Ser29) Polyclonal Antibody

Catalog # :

PA5-101035

Quantity :

100 uL

Price :

US 414.00

Clonality :

Polyclonal

Purity :

sequential chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:1,000-1:3,000

Species :

Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

-20 C

Description :

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically, double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.

Immunogen :

A synthesized peptide derived from human TP53BP1(Accession Q12888), corresponding to amino acid residues around phosphorylated Ser29.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:500, Western Blot: 1:1,000-1:3,000

Aliases :

53BP1; FLJ41424; m53BP1; MGC138366; murine p53-binding protein; p202; p53-binding protein 1; p53BP1; TDRD30; TP53; TP53-binding protein 1; Tp53bp1; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; Trp53bp1; tumor protein 53-binding protein, 1; tumor protein p53 binding protein 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1