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antibody

KDEL Receptor Pan Polyclonal Antibody

PA5-101011

100 uL

US 454.00

polyclonal

domestic rabbit

nonconjugated

human, mouse, rat

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

KDEL Receptor Pan Polyclonal Antibody

PA5-101011

100 uL

US 454.00

Polyclonal

Affinity chromatography

Rabbit

Human, Mouse, Rat

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:1,000-1:3,000

Human, Mouse, Rat

IgG

-20 C

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.

A synthesized peptide derived from human KDELR1(Accession P24390), corresponding to amino acid residues N89-S139.

Liquid

Immunocytochemistry: 1:100-1:500, Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:1,000-1:3,000

(Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2; 1110007A14Rik; 8030486F04Rik; AI173274; AW215843; BEST:CK00230; CG5183; CG5183-PA; CG5183-PB; CG5183-PC; CK00230; Dmel CG5183; Dmel_CG5183; dmErd2; ELP-1; ER lumem protein retaining receptor 2; ER lumen protein retaining receptor; ER lumen protein retaining receptor 1; ER lumen protein retaining receptor 2; ER lumen protein retaining receptor 3; ER lumen protein-retaining receptor; ER lumen protein-retaining receptor 1; ER lumen protein-retaining receptor 2; ER lumen protein-retaining receptor 3; ERD2; Erd2.1; ERD2.2; ERD23; ERD2L3; ERD-2-like protein; ERD2-like protein 1; ergr15; HDEL; hypothetical protein; I79_001653; I79_020931; I79_023963; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3; KDEL endoplasmic reticulum protein retention receptor 1; KDEL endoplasmic reticulum protein retention receptor 2; KDEL endoplasmic reticulum protein retention receptor 2 L homeolog; KDEL endoplasmic reticulum protein retention receptor 3; KDEL receptor; KDEL receptor 1; KDEL receptor 2; KDEL receptor 3; KDEL receptor-like protein; KDELR; Kdelr1; Kdelr2; kdelr2.L; KDELR3; KDEL-receptor; KdelR-PA; KdelR-PB; KdelR-PC; l(2)31Em; l(2)k00311; lethal (2) 31Em; PM23; Putative MAPK-activating protein PM23; RCJMB04_8l23; Unknown (protein for MGC:128955); XELAEV_18045328mg