IP3 Receptor 1 Polyclonal Antibody | Invitrogen PA3-901A product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

IP3 Receptor 1 Polyclonal Antibody

catalog :

PA3-901A

quantity :

100 uL

price :

US 419.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

citations: 2

Reference
Filadi R, De Mario A, Audano M, Romani P, Pedretti S, Cardenas C, et al. Sustained IP3-linked Ca2+ signaling promotes progression of triple negative breast cancer cells by regulating fatty acid metabolism. Front Cell Dev Biol. 2023;11:1071037 pubmed publisher
Volpe P, Bosutti A, Nori A, Filadi R, Gherardi G, Trautmann G, et al. Nerve-dependent distribution of subsynaptic type 1 inositol 1,4,5-trisphosphate receptor at the neuromuscular junction. J Gen Physiol. 2022;154: pubmed publisher

product information

Product Type :

Antibody

Product Name :

IP3 Receptor 1 Polyclonal Antibody

Catalog # :

PA3-901A

Quantity :

100 uL

Price :

US 419.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: Assay-dependent

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.

Immunogen :

Synthetic peptide corresponding to residues N(1829) K K K D D E V D R D A P S R K K A K E(1848) of human IP3 Receptor Type I.

Format :

Liquid

Applications w/Dilutions :

Western Blot: Assay-dependent

Aliases :

ACV; CLA4; D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor, type 1; inositol 1,4,5-trisphosphate receptor 1; inositol 1,4,5-trisphosphate receptor type 1; inositol 1,4,5-trisphosphate receptor, type 1; inositol 1,4,5-trisphosphate-binding protein P400; InsP>3<R type I; Insp3r; InsP3R type I; insP3R1; IP3 receptor; IP3 receptor isoform 1; Ip3r; IP-3-R; IP3R 1; IP3R1; Itpr1; Itpr-1; opisthotonus; opt; P400; Pcd6; Pcp1; Pcp-1; PPP1R94; protein PCD-6; protein phosphatase 1, regulatory subunit 94; Purkinje cell protein 1; SCA15; SCA16; SCA29; SI-SIII-SIIA; Type 1 inositol 1,4,5-trisphosphate receptor; type 1 InsP3 receptor