KCNH2 Polyclonal Antibody | Invitrogen PA3-860 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

KCNH2 Polyclonal Antibody

catalog :

PA3-860

quantity :

100 uL

price :

US 451.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation

product information

Product Type :

Antibody

Product Name :

KCNH2 Polyclonal Antibody

Catalog # :

PA3-860

Quantity :

100 uL

Price :

US 451.00

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:3000, Immunoprecipitation: 1:100, Western Blot: 1:20,000

Species :

Human

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

Human ether-a-go-go related gene (HERG) encodes the pore-forming alpha subunit of the delayed rectifier potassium channel IKr. There are two N-terminal splice variants of HERG include the full-length isoform 1 alpha and the shorter isoform 1 beta. Isoform 1 beta lacks the PAS motif and deactivates at a faster rate than isoform 1alpha. Residues within the C-terminal play a role in channel expression and channel gating, including voltage-dependent activation. HERG is expressed in the heart and is more abundantly expressed in the ventricles than in the atria. Mutations in the gene encoding HERG increase beat-to-beat variability and early after depolarization. These fluctuations facilitate the genesis and propagation of premature heartbeats associated with inheritable long QT syndrome type 2 and short QT syndrome type 1.

Immunogen :

Fusion Protein of HERG encoding 181 amino acid residues from the C-terminus.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:3000, Immunoprecipitation: 1:100, Western Blot: 1:20,000

Aliases :

AI326795; cerg; c-ERG; cERG; ether-a-go-go related member 2; delayed rectifier potassium channel; derg; Eag homolog; eag related protein 1; eag-related gene; eag-related protein 1; ERG; ERG1; ERG-1; ether-a-go-go related gene potassium channel 1; ether-a-go-go related protein; ether-a-go-go-related gene potassium channel 1; ether-a-go-go-related potassium channel protein; ether-a-go-go-related protein 1; gp-erg; HERG; H-ERG; HERG1; HERG-1; KCNH2; Kv11.1; LQT; Lqt2; M-erg; Merg1; M-erg1; merg1a; merg1b; potassium channel; potassium channel protein ERG; potassium channel protein ERG long isoform; potassium channel protein ERG short isoform; potassium channel, voltage gated eag related subfamily H, member 2; potassium voltage-gated channel subfamily H member 2; potassium voltage-gated channel, subfamily H (eag-related), member 2; ra-erg; RERG; r-ERG; SQT1; ventricular ERG K+ channel subunit; voltage-gated potassium channel 11.1; voltage-gated potassium channel subunit Kv11.1; voltage-gated potassium channel variant 3; voltage-gated potassium channel, subfamily H, member 2