This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
IFIT2 Polyclonal Antibody
catalog :
PA3-845
quantity :
100 µL
price :
US 466
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig s9i
Daniels B, Jujjavarapu H, Durrant D, Williams J, Green R, White J, et al. Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection. J Clin Invest. 2017;127:843-856 pubmed publisher
Freed S, Baldi D, Snow J, Athen S, Guinn Z, Pinkerton T, et al. MEK/ERK MAP kinase limits poly I:C-induced antiviral gene expression in RAW264.7 macrophages by reducing interferon-beta expression. FEBS Lett. 2021;595:2665-2674 pubmed publisher
Chemudupati M, Kenney A, Smith A, Fillinger R, Zhang L, Zani A, et al. Butyrate Reprograms Expression of Specific Interferon-Stimulated Genes. J Virol. 2020;94: pubmed publisher
Guinn Z, Petro T. Interferon regulatory factor 3 plays a role in macrophage responses to interferon-γ. Immunobiology. 2019;: pubmed publisher
Guinn Z, Brown D, Petro T. Activation of IRF3 contributes to IFN-? and ISG54 expression during the immune responses to B16F10 tumor growth. Int Immunopharmacol. 2017;50:121-129 pubmed publisher
Deng X, Hackbart M, Mettelman R, O Brien A, Mielech A, Yi G, et al. Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages. Proc Natl Acad Sci U S A. 2017;114:E4251-E4260 pubmed publisher
Prigge J, Hoyt T, Dobrinen E, Capecchi M, Schmidt E, Meissner N. Type I IFNs Act upon Hematopoietic Progenitors To Protect and Maintain Hematopoiesis during Pneumocystis Lung Infection in Mice. J Immunol. 2015;195:5347-57 pubmed publisher
product information
Product Type :
Antibody
Product Name :
IFIT2 Polyclonal Antibody
Catalog # :
PA3-845
Quantity :
100 µL
Price :
US 466
Clonality :
Polyclonal
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 1:100-1:250, Western Blot: 1:1,000-1:2,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
IFIT2 belongs to the IFIT family. It contains 6 TPR repeats. IFIT genes comprise a large family with three (Ifit1, Ifit2, and Ifit3) and four (IFIT1, IFIT2, IFIT3, and IFIT5) members in mice and humans, respectively. IFITproteins are produced in human body that are supposed to confer immunity against viral infection. These proteins are generally produced during viral infection, Interferon (IFN) treatment, and during pathogen recognition (Pathogen associated molecular pattern recognition) byimmune systemduring infections.
Immunogen :
Bacterially expressed full-length mouse p54 protein
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100-1:250, Western Blot: 1:1,000-1:2,000
Aliases :
AV302338; cig42; CIG-42; G10P2; Garg39; GARG-39; Glucocorticoid-attenuated response gene 39 protein; IFI54; IFI-54; IFI-54K; Ifit2; IFIT-2; interferon induced protein with tetratricopeptide repeats 2; Interferon, alpha-inducible protein (MW 54kD); interferon-induced 54 kDa protein; interferon-induced protein 54; interferon-induced protein with tetratricopeptide repeats 2; ISG54; ISG-54 K; ISG-54K; P54
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA