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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
PPAR gamma Polyclonal Antibody
catalog :
PA3-821A
quantity :
100 uL
price :
US 465.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 17
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:100; fig 4
Jung J, Bache Wiig M, Provenzano P, Ogle B. Heterogeneous Differentiation of Human Mesenchymal Stem Cells in 3D Extracellular Matrix Composites. Biores Open Access. 2016;5:37-48 pubmed publisher
  • western blot; human; 1:1000; fig 1
  • immunohistochemistry; mouse; 1:200; fig 2
Dickey A, Pineda V, Tsunemi T, Liu P, Miranda H, Gilmore Hall S, et al. PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically. Nat Med. 2016;22:37-45 pubmed publisher
Conway J, Din xe7 D, Follain G, Paavolainen O, Kaivola J, Bostr xf6 m P, et al. IGFBP2 secretion by mammary adipocytes limits breast cancer invasion. Sci Adv. 2023;9:eadg1840 pubmed publisher
Oliveira F, Freire V, Coelho S, Meuren L, Palmeira J, Cardoso A, et al. ZIKV Strains Elicit Different Inflammatory and Anti-Viral Responses in Microglia Cells. Viruses. 2023;15: pubmed publisher
Llibre A, Smith N, Rouilly V, Musvosvi M, Nemes E, Posseme C, et al. Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses. Front Immunol. 2022;13:897193 pubmed publisher
Khalaj K, Figueira R, Antounians L, Gandhi S, Wales M, Montalva L, et al. Treatment with Amniotic Fluid Stem Cell Extracellular Vesicles Promotes Fetal Lung Branching and Cell Differentiation at Canalicular and Saccular Stages in Experimental Pulmonary Hypoplasia Secondary to Congenital Diaphragmatic Hernia. Stem Cells Transl Med. 2022;11:1089-1102 pubmed publisher
Arulkumar R, Jung H, Noh S, Park D, Chung H. Cheonggukjang-Specific Component 1,3-Diphenyl-2-Propanone as a Novel PPARα/γ Dual Agonist: An In Vitro and In Silico Study. Int J Mol Sci. 2021;22: pubmed publisher
Jetton T, Flores Bringas P, LEAHY J, Gupta D. SetD7 (Set7/9) is a novel target of PPARγ that promotes the adaptive pancreatic β-cell glycemic response. J Biol Chem. 2021;297:101250 pubmed publisher
Childers R, Lucchesi P, Gooch K. Decreased Substrate Stiffness Promotes a Hypofibrotic Phenotype in Cardiac Fibroblasts. Int J Mol Sci. 2021;22: pubmed publisher
Wilson H, Stanton D, Rellick S, Geldenhuys W, Pistilli E. Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG. Am J Physiol Cell Physiol. 2021;320:C577-C590 pubmed publisher
Tharp W, Gupta D, Sideleva O, Deacon C, Holst J, Elahi D, et al. Effects of Pioglitazone on Glucose-Dependent Insulinotropic Polypeptide-Mediated Insulin Secretion and Adipocyte Receptor Expression in Patients With Type 2 Diabetes. Diabetes. 2020;69:146-157 pubmed publisher
Mousavi M, Shahverdi A, Drevet J, Akbarinejad V, Esmaeili V, Sayahpour F, et al. Peroxisome Proliferator-Activated Receptors (PPARs) levels in spermatozoa of normozoospermic and asthenozoospermic men. Syst Biol Reprod Med. 2019;65:409-419 pubmed publisher
Wilson H, Rhodes K, Rodriguez D, Chahal I, Stanton D, BOHLEN J, et al. Human Breast Cancer Xenograft Model Implicates Peroxisome Proliferator-activated Receptor Signaling as Driver of Cancer-induced Muscle Fatigue. Clin Cancer Res. 2018;: pubmed publisher
Kohan Ghadr H, Kilburn B, Kadam L, Johnson E, Kolb B, Rodriguez Kovacs J, et al. Rosiglitazone augments antioxidant response in the human trophoblast and prevents apoptosis†. Biol Reprod. 2019;100:479-494 pubmed publisher
Kim S, Xie Y, Nguyen P, Bui V, Huynh K, Kang J, et al. PPARγ regulates meibocyte differentiation and lipid synthesis of cultured human meibomian gland epithelial cells (hMGEC). Ocul Surf. 2018;16:463-469 pubmed publisher
Xue L, Li Y, Chen J. Duration of simulated microgravity affects the differentiation of mesenchymal stem cells. Mol Med Rep. 2017;15:3011-3018 pubmed publisher
Liu Y, AYERS S, Milanesi A, Teng X, Rabi S, Akiba Y, et al. Thyroid hormone receptor sumoylation is required for preadipocyte differentiation and proliferation. J Biol Chem. 2015;290:7402-15 pubmed publisher
product information
Product Type :
Antibody
Product Name :
PPAR gamma Polyclonal Antibody
Catalog # :
PA3-821A
Quantity :
100 uL
Price :
US 465.00
Clonality :
Polyclonal
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 1:250, Western Blot: 1:500-1:1,500
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
-20 C, Avoid Freeze/Thaw Cycles
Description :
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
Immunogen :
Synthetic peptide corresponding to residues M(284) M G E D K I K F K H I T P L(298) of mouse PPAR gamma 2.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:250, Western Blot: 1:500-1:1,500
Aliases :
CIMT1; GLM1; HUMPPARG; NR1C3; nuclear hormone receptor; nuclear hormone receptor; PPARG; Nuclear receptor subfamily 1 group C member 3; nuclear receptor transcription factor; OTTHUMP00000185032; OTTHUMP00000185036; peroxisome proliferative activated receptor, gamma; peroxisome proliferative activated receptor, gamma-2; peroxisome proliferator; peroxisome proliferator activated receptor; peroxisome proliferator activated receptor gamma; peroxisome proliferator activated receptor gamma 1; peroxisome proliferator activated receptor gamma 2; peroxisome proliferator activated receptor gamma 4; peroxisome proliferator activated receptor gamma-1; peroxisome proliferator activated receptor gamma-2; peroxisome proliferator activatived receptor gamma; peroxisome proliferator activator receptor, gamma; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor; peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma 1; peroxisome proliferator-activated receptor gamma 1a; peroxisome proliferator-activated receptor gamma 1-a; peroxisome proliferator-activated receptor gamma 1b; peroxisome proliferator-activated receptor gamma 1-b; peroxisome proliferator-activated receptor gamma 1c; peroxisome proliferator-activated receptor gamma 1d; peroxisome proliferator-activated receptor gamma 2; peroxisome proliferator-activated receptor-gamma; peroxisome proliferator-activated receptor-gamma 2; peroxisome proliferator-cctivated receptor gamma 1; PPAR gamma; PPAR gamma 1; PPAR gamma 3; Pparg; PPARG1; PPARG2; PPARgamma; PPAR-gamma; PPARgamma2; PPAR-gamma2; PPARy; proliferator activated gamma; transcription factor
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA